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Yasser EL-Manzalawy | Assistant Research Professor

Center for Big Data Analytics and Discovery Informatics
College of Information Sciences and Technology
E349 Westgate Building
Penn State University
University Park, PA 16802
Office Phone: (814)-863-8832

Research interests

My research interests aim at analyzing, understanding, and making sense of (big) data in life and health sciences. Specifically, my research is targeted towards: i) deciphering the underlying mechanisms controlling different types of macromolecular interactions; ii) developing innovative algorithms and tools for enabling and promoting data-intensive, collaborative, and translational research in precision medicine, microbiome research, and health informatics; iii) developing and applying integrative informatics methodologies to enable and accelerate translational science. A common theme of my previous research in bioinformatics is the development and the application of state-of-the-art machine learning algorithms to decipher the underlying mechanisms controlling different types of macromolecular interactions including: antibody-antigen recognition; major histocompatibility complex (MHC)-restricted antigen recognition; protein-protein interactions; protein-nucleic acid interactions; and promoter recognition by RNA polymerase. My current and long-term research goals entail the development of more sophisticated, integrative, and longitudinal algorithms, frameworks, and analyses of biomedical and health data.